Acetonitrile

Xem hình lớn Code:00683 Code: 00683 Đóng gói: 2.5L Hãng sản xuất: Fluka

Acetonitrile

CHROMASOLV^® (gradient grade +), suitable for PAH analysis, ≥99.9% (GC)

Synonym: ACN, Methyl cyanide

• CAS Number 75-05-8

• Linear Formula CH₃CN

• Molecular Weight 41.05

•  Beilstein Registry Number 741857

•  EC Number 200-835-2

•  MDL number MFCD00001878

•  PubChem Substance ID 24844939

•  eCl@ss 39031501

• Properties

  Related Categories	Acetonitrile and Acetonitrile Solutions, Analytical Reagents, Analytical/Chromatography, Chromatography Reagents & Solvents, HPLC & UHPLC Solvents, HPLC Gradient Grade Solvents, Solvent by Type, Solvents
  grade	CHROMASOLV® (gradient grade +)
  	suitable for PAH analysis
  vapor density	1.41 (vs air)
  vapor pressure	72.8 mmHg ( 20 °C)
  assay	≥99.9% (GC)
  autoignition temp.	973 °F
  shelf life	limited shelf life, expiry date on the label
  expl. lim.	16 %
  impurities	≤0.0005% free alkali (as NH3)
  	≤0.005% free acid (as CH3COOH)
  	≤0.02% water
  	≤1 ppb fluorescence (quinine), Em 250-550nm, Ex 200-450nm
  evapn. residue	≤0.001%
  refractive index	n20/D 1.344(lit.)
  	n20/D 1.344
  bp	81-82 °C(lit.)
  mp	−48 °C(lit.)
  density	0.786 g/mL at 25 °C(lit.)
  absorption	absorption/210 nm <1.5 mAU
  	absorption/254 nm <0.2 mAU
  λ	1 cm path, H2O reference
  UV absorption	λ: 200 nm Amax: ≤0.04
  	λ: 215 nm Amax: ≤0.01
  	λ: 230 nm Amax: ≤0.005

  Description

  Application

  Aetonitrile may be used for the following studies:
  • Removal of residues of nonpolar organochlorine insecticides (OCs) and other nonpolar pesticides from foods (non) by Mills method.¹
  • Dispersive solid-phase extraction (dispersive-SPE) of pesticide residues from fruits and vegetables.¹
  • As solvent to investigate the reaction mechanisms of the formation of extremely unstable copper(II) CuCl₄^2-chlorocomplexes.²
  • As polar solvent in the Resonance Raman (RR) spectroscopic characterization of structures and environments of the protein-bound peridinins (Pers) and chlorophylls (Chls) a/c₂.³
  • Used in mobile phase during the LC-MS quantification of the biologically active constituents of Radix Angelicae Pubescentis.⁴
  • Used to constitute 20mM sodium phosphate buffer, which is employed in mobile phase for the UV spectroscopic, reverse phase HPLC (RP-HPLC) and HPTLC determination of stavudine (SV), lamivudine (LV) and nevirapine (NV) in tablets.⁵
  • To compose the gradient system for the HPLC detection of diphenylmethane diisocyanate, a polymeric degradation product.⁶
  

  General description

  Acetonitrile (MeCN) is a polar solvent³ and has high dielectric constant (37.5).⁷ Its purification to obtain different grades for use in different studies (polarography, spectroscopy, etc) have been reported by many researchers.⁷

  Legal Information

  CHROMASOLV is a registered trademark of Sigma-Aldrich Laborchemikalien GmbH

• Safety Information

  Symbol 

    GHS02, GHS07

  Signal word 

  Danger

  Hazard statements 

  H225-H302 + H312 + H332-H319

  Precautionary statements 

  P210-P280-P305 + P351 + P338

  Personal Protective Equipment 

  Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter

  RIDADR 

  UN 1648 3 / PGII

  WGK Germany 

  2

  RTECS 

  AL7700000

  Flash Point(F) 

  35.6 °F

  Flash Point(C) 

  2 °C