Fluconazole

Xem hình lớn Code:F8929 Code: F8929 Đóng gói: 100mg Hãng sản xuất: Sigma

Fluconazole

≥98% (HPLC), powder

Synonym: 2-(2,4-Difluorophenyl)-1,3-bis(1H-1,2,4-triazol-1-yl)propan-2-ol

• CAS Number 86386-73-4

• Empirical Formula (Hill Notation) C₁₃H₁₂F₂N₆O

• Molecular Weight 306.27

•  MDL number MFCD00274549

•  PubChem Substance ID 24724485

  Properties

  Related Categories	Antibiotics, Antibiotics A to Z, Antibiotics A-F, Antifungal, Approved Therapeutics/Drug Candidates, Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Biochemicals and Reagents, Cell Biology, Cell Signaling and Neuroscience, Diversification Ready Pharma-Developed Compounds, F, Immune Cell Signaling and Blood, Immune System Regulation, Immunomodulators and Antibiotics, Inhibits an Enzyme, Mechanism of Action, Pfizer Compounds, Spectrum of Activity
  assay	≥98% (HPLC)
  form	powder
  solubility	DMSO: soluble5 mg/mL
  Mode of action	enzyme | inhibits
  originator	Pfizer
  storage temp.	room temp
  Gene Information	human ... CYP1A2(1544)

  Description

  Packaging

  100 mg in glass bottle

  Biochem/physiol Actions

  Fluconazole is an antifungal agent. It is highly selective inhibitor of fungal cytochrome P-450 sterol C-14 α-demethyllation. Fluconazole is a potent inhibitor of CYP2C9. Fluconazole interferes with fungal ergosterol synthesis and downregulates the metallothionein gene.

  Features and Benefits

  This compound is a featured product for ADME Tox research. Click here to discover more featured ADME Tox products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

  This compound was developed by Pfizer. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, .

  Other Notes

  Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. F8929.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.

  Safety Information

  Symbol 

    GHS07

  Signal word 

  Warning

  Hazard statements 

  H302-H315-H319-H335

  Precautionary statements 

  P261-P305 + P351 + P338

  Personal Protective Equipment 

  dust mask type N95 (US), Eyeshields, Gloves

  RIDADR 

  NONH for all modes of transport

  WGK Germany 

  3

  RTECS 

  XZ4810000